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KMID : 0363219950330040698
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Korean Journal of Dermatology
1995 Volume.33 No. 4 p.698 ~ p.704
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A Study on the Blood Lipid, Lipoprotein, Apolipordein Measuriement acid the Difference according to Family History in Psoriasis Patients
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Abstract
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Background:
@EN Psoriasis is a disease of unknown etiology. Disturbances in lipid metabolism have been suggested as a possible pathogenetic mechanism.
@ES Objective:
@EN The study was performed to investigate the blood lipid, lipoprotein and apolipo protein levels and their difference according to family history in Korean psoriasis patients.
@ES Methods:
@EN Blood samples from seventy three psoriasis patients and twenty three normal persons were measured for total cholesterol(TC) VLDL-cholesterol(VLDL-C), LDL-cholesterol(LDL-C), HDL-cholesterol(HDL-C), lipoprotein(a)(LPA), triglyceride(TG),
apolipoprotein A-I(APO-AI), and apolipoprotein B(APO-B), Psoriasis patients were divided according to their family history of psoriasis.
@ES Results:
@EN Compared to controls, TC, LDL-C, LPA, TG, APO-B were significantly elevated in psoriasis patients. Mean values of LPA and APO-B in psoriasis group were above normal range. VLDL-C were significantly elevated only in female patients. There was
a
tendency for psoriasis patients with family history to have higher values than those without family history.
@ES Conlusion:
@EN TC, LDL-C, LPA, TG, APO-B was increased in psoriasis, especially in the patients with family history, compared to control. It is recommended that we must pay attention to the possible risk for the development of cardiac or cerebral vascular
disease
in psoriasis patients, es peciany in the presence of family history of psoriasis.
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